학술논문
Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2
Document Type
article
Author
Source
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Subject
Language
English
ISSN
2399-3642
Abstract
Specific small molecule RXFP2 agonists with favorable pharmacokinetic properties induce gubernacular invagination in mouse embryos, increase mineralization activity in human osteoblasts in vitro, and improve bone trabecular parameters in adult mice.