학술논문

The Quartet Data Portal: integration of community-wide resources for multiomics quality control
Document Type
article
Source
Genome Biology, Vol 24, Iss 1, Pp 1-19 (2023)
Subject
Quartet Data Portal
Multiomics
Quartet Project
Quality control
Reference materials
Reference datasets
Biology (General)
QH301-705.5
Genetics
QH426-470
Language
English
ISSN
1474-760X
Abstract
Abstract The Quartet Data Portal facilitates community access to well-characterized reference materials, reference datasets, and related resources established based on a family of four individuals with identical twins from the Quartet Project. Users can request DNA, RNA, protein, and metabolite reference materials, as well as datasets generated across omics, platforms, labs, protocols, and batches. Reproducible analysis tools allow for objective performance assessment of user-submitted data, while interactive visualization tools support rapid exploration of reference datasets. A closed-loop “distribution-collection-evaluation-integration” workflow enables updates and integration of community-contributed multiomics data. Ultimately, this portal helps promote the advancement of reference datasets and multiomics quality control.