학술논문

Unmet Needs in TAVR: Conduction Disturbances and Management of Coronary Artery Disease
Document Type
article
Source
Journal of Clinical Medicine, Vol 11, Iss 21, p 6256 (2022)
Subject
transcatheter aortic valve replacement
transcatheter aortic valve implantation
coronary artery disease
myocardial infarction
coronary access
coronary revascularization
Medicine
Language
English
ISSN
2077-0383
Abstract
Over the past two decades, transcatheter aortic valve replacement (TAVR) swiftly evolved from a disrupting technology towards mainstream therapy in the field of severe symptomatic aortic stenosis. A series of randomized evaluations established its role in treating severe aortic stenosis patients across all surgical risk categories, paving the way for an extension of its indications to younger low-risk patients with a longer life expectancy. Therefore, managing comorbidities and limiting procedural complications, which may affect long-term outcomes, is of paramount importance. Among those, new-onset conduction disturbances and concomitant coronary artery disease remain two of the most debated issues. In the present review, we will discuss the incidence, prognostic impact, and unmet needs of patients with post-TAVR new-onset conduction disturbances and the ongoing challenges posed by the management of concomitant coronary artery disease.