학술논문
Effect of ABCA1-R219K Polymorphism in Serum Lipid Parameters in Patients under Statin Therapy Visiting Tertiary Cardiac Center of Nepal
Document Type
article
Author
Source
Journal of Laboratory Physicians, Vol 15, Iss 04, Pp 510-517 (2023)
Subject
Language
English
ISSN
0974-2727
0974-7826
0974-7826
Abstract
Introduction ATP-binding cassette transporter A1 (ABCA1) encoded by ABCA1 gene is one of the important protein involved in lipid metabolism. The effect of statin therapy on dyslipidemia varies among individuals and it may be due to different genetic polymorphism. The R219K polymorphism of ABCA1 gene is found to have a significant role in the response of statin.