학술논문
Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma
Document Type
article
Author
Mrinal M. Gounder; Narasimhan P. Agaram; Sally E. Trabucco; Victoria Robinson; Richard A. Ferraro; Sherri Z. Millis; Anita Krishnan; Jessica Lee; Steven Attia; Wassim Abida; Alexander Drilon; Ping Chi; Sandra P. D’ Angelo; Mark A. Dickson; Mary Lou Keohan; Ciara M. Kelly; Mark Agulnik; Sant P. Chawla; Edwin Choy; Rashmi Chugh; Christian F. Meyer; Parvathi A. Myer; Jessica L. Moore; Ross A. Okimoto; Raphael E. Pollock; Vinod Ravi; Arun S. Singh; Neeta Somaiah; Andrew J. Wagner; John H. Healey; Garrett M. Frampton; Jeffrey M. Venstrom; Jeffrey S. Ross; Marc Ladanyi; Samuel Singer; Murray F. Brennan; Gary K. Schwartz; Alexander J. Lazar; David M. Thomas; Robert G. Maki; William D. Tap; Siraj M. Ali; Dexter X. Jin
Source
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Comprehensive molecular profiles are required to understand and treat sarcomas, which comprise more than 70 different subtypes. Here, the authors profile the genomic landscape of 7494 sarcomas across 44 histologies using targeted panel sequencing and identify potential therapeutic targets.