학술논문
Successful Treatment of Balamuthia mandrillaris Granulomatous Amebic Encephalitis with Nitroxoline
Document Type
article
Author
Source
Emerging Infectious Diseases, Vol 29, Iss 1, Pp 197-201 (2023)
Subject
Language
English
ISSN
1080-6040
1080-6059
1080-6059
Abstract
A patient in California, USA, with rare and usually fatal Balamuthia mandrillaris granulomatous amebic encephalitis survived after receiving treatment with a regimen that included the repurposed drug nitroxoline. Nitroxoline, which is a quinolone typically used to treat urinary tract infections, was identified in a screen for drugs with amebicidal activity against Balamuthia.