학술논문

Off-label intravenous thrombolysis for early recurrent brain embolism associated with aortic arch thrombus
Document Type
article
Source
Neurological Research and Practice, Vol 3, Iss 1, Pp 1-3 (2021)
Subject
Off-label thrombolysis
Aortic arch thrombus
Stroke
Brain embolism
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Language
English
ISSN
2524-3489
Abstract
Abstract Safety data of intravenous thrombolysis (IVT) in presence of aortic arch thrombus is scant. Furthermore, IVT is debatable in patients with prior recent stroke. We present a 51-year-old woman with recurrent major infarction 5 days after a minor left MCA territory stroke. She had a floating aortic arch thrombus and she was treated safely and effectively with off-label IVT. Patients with small infarct volumes and mild/no residual neurological deficits after an initial stroke might be considered for IVT in case of early recurrence. IVT may be reasonable in a context of acute severely disabling stroke associated with aortic arch thrombus.