학술논문
Genomics and phenomics of body mass index reveals a complex disease network
Document Type
article
Author
Jie Huang; Jennifer E. Huffman; Yunfeng Huang; Ítalo Do Valle; Themistocles L. Assimes; Sridharan Raghavan; Benjamin F. Voight; Chang Liu; Albert-László Barabási; Rose D. L. Huang; Qin Hui; Xuan-Mai T. Nguyen; Yuk-Lam Ho; Luc Djousse; Julie A. Lynch; Marijana Vujkovic; Catherine Tcheandjieu; Hua Tang; Scott M. Damrauer; Peter D. Reaven; Donald Miller; Lawrence S. Phillips; Maggie C. Y. Ng; Mariaelisa Graff; Christopher A. Haiman; Ruth J. F. Loos; Kari E. North; Loic Yengo; George Davey Smith; Danish Saleheen; J. Michael Gaziano; Daniel J. Rader; Philip S. Tsao; Kelly Cho; Kyong-Mi Chang; Peter W. F. Wilson; VA Million Veteran Program; Yan V. Sun; Christopher J. O’Donnell
Source
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Elevated body mass index is heritable and associated with many health conditions that impact morbidity and mortality. Here, the authors identify greater than 900 genetic loci for body mass index (BMI) and find over 300 diagnoses associated with increasing BMI.