학술논문

Laboratory diagnosis of antiphospholipid syndrome
Document Type
article
Source
Reumatismo, Vol 59, Iss 3, Pp 187-191 (2011)
Subject
Medicine
Internal medicine
RC31-1245
Language
English
Italian
ISSN
0048-7449
2240-2683
Abstract
Diagnosis of antiphosholipid syndrome (APS) is based on laboratory detection of antiphospholipid (aPL) antibodies in patients with documented thrombosis or in women with pregnancy morbidity. Recently, both clinical and laboratory criteria were revised on the basis of an international consensus conference held in Sydney (1). The previous international consensus statement of one clinical and one laboratory criterion to diagnose APS was maintained (2) but time-lapse between the previous thromboembolism and laboratory diagnosis should not exceed 5 years. Moreover, laboratory tests should not be performed in the 12 weeks following the event to avoid any interference of the acute phase of the disease. Thus, laboratory evaluation of venous thromboembolism (VTE) should not be requested during the hospital stay as tests may be false-positive with no influence on the treatment regimen...