학술논문

Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential
Document Type
article
Source
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Subject
Science
Language
English
ISSN
2041-1723
Abstract
Epigenetic reprogramming of the androgen receptor (AR) has been identified as an important process driving prostate cancer (PCa) progression. Here, the authors analyze the role of AR chromatin binding heterogeneity in PCa clinical outcomes, metastasis and relapse.