학술논문
Diastereoselective Mannich reactions of pseudo-C2-symmetric glutarimide with activated imines
Document Type
article
Source
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2473-2477 (2017)
Subject
Language
English
ISSN
1860-5397
Abstract
As an extension of the boron enolate-based aldol reactions, the oxazolidinone-installed bisimide 1a from 3-(trifluoromethyl)glutaric acid was employed for Mannich reactions with tosylated imines 2 as electrophiles to successfully obtain the corresponding adducts in a stereoselective manner.