학술논문

Extracellular Vesicles, Inflammation, and Cardiovascular Disease
Document Type
article
Source
Cells, Vol 11, Iss 14, p 2229 (2022)
Subject
extracellular vesicles
exosomes
microvesicles
inflammation
innate immunity
adaptive immunity
Cytology
QH573-671
Language
English
ISSN
2073-4409
Abstract
Cardiovascular disease is a leading cause of death worldwide. The underlying mechanisms of most cardiovascular disorders involve innate and adaptive immune responses, and extracellular vesicles are implicated in both. In this review, we describe the mechanistic role of extracellular vesicles at the intersection of inflammatory processes and cardiovascular disease. Our discussion focuses on atherosclerosis, myocardial ischemia and ischemic heart disease, heart failure, aortic aneurysms, and valvular pathology.