학술논문
Underwater endoscopic mucosal resection: a new endoscopic method for resection of rectal neuroendocrine tumor grade 1 (carcinoid) ≤ 10 mm in diameter
Document Type
article
Author
Takeshi Yamashina; Takehiko Tumura; Takanori Maruo; Takayuki Matsumae; Hiroyuki Yoshida; Gensho Tanke; Mio Taki; Manabu Fukuhara; Yoshito Kimura; Azusa Sakamoto; Shinichiro Henmi; Yugo Sawai; Sumio Saito; Norihiro Nishijima; Akihiro Nasu; Hideyuki Komekado; Masanori Asada; Ryuichi Kita; Toru Kimura; Yukio Osaki
Source
Endoscopy International Open, Vol 06, Iss 01, Pp E111-E114 (2018)
Subject
Language
English
ISSN
2364-3722
2196-9736
2196-9736
Abstract
Background and study aims Rectal neuroendocrine tumors grade 1 (NET G1; carcinoid) ≤ 10 mm in diameter often extend into the submucosa, making their complete histological resection difficult using endoscopic techniques. Endoscopic submucosal resection with a ligation device (ESMR-L) and endoscopic submucosal dissection (ESD) are commonly used to overcome these difficulties. We also previously reported that underwater endoscopic mucosal resection (UEMR) could facilitate resection of rectal NET G1. This study aimed to evaluate the safety and efficacy of UEMR for removing rectal NET G1 ≤ 10 mm in diameter. 6 consecutive patients with rectal NET G1 ≤ 10 mm in diameter underwent UEMR at our hospital. The rate of en bloc resection was 100 %, and the rate of R0 resection was 83 %. The median procedure time was 8 min (range 5 – 12 min). No perforations or delayed bleeding occurred in this study. In conclusion, UEMR allows the safe and reliable resection of rectal NET G1 ≤ 10 mm in diameter with comparable results to ESMR-L or ESD, including high en bloc and R0 resection rates with no increase in significant adverse events. A multicenter trial is required to confirm the validity of the present results.