학술논문
Genome-wide CRISPR screen for HSV-1 host factors reveals PAPSS1 contributes to heparan sulfate synthesis
Document Type
article
Author
Source
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Subject
Language
English
ISSN
2399-3642
Abstract
A genome-wide CRISPR screen for HSV-1 host factors using near-haploid HAP1 cells revealed PAPSS1 as an essential factor for heparan sulfate biosynthesis and HSV-1 infection, and identified several other host factors also involved in both processes.