학술논문
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
Document Type
article
Author
Leanne K. Küpers; Claire Monnereau; Gemma C. Sharp; Paul Yousefi; Lucas A. Salas; Akram Ghantous; Christian M. Page; Sarah E. Reese; Allen J. Wilcox; Darina Czamara; Anne P. Starling; Alexei Novoloaca; Samantha Lent; Ritu Roy; Cathrine Hoyo; Carrie V. Breton; Catherine Allard; Allan C. Just; Kelly M. Bakulski; John W. Holloway; Todd M. Everson; Cheng-Jian Xu; Rae-Chi Huang; Diana A. van der Plaat; Matthias Wielscher; Simon Kebede Merid; Vilhelmina Ullemar; Faisal I. Rezwan; Jari Lahti; Jenny van Dongen; Sabine A. S. Langie; Tom G. Richardson; Maria C. Magnus; Ellen A. Nohr; Zongli Xu; Liesbeth Duijts; Shanshan Zhao; Weiming Zhang; Michelle Plusquin; Dawn L. DeMeo; Olivia Solomon; Joosje H. Heimovaara; Dereje D. Jima; Lu Gao; Mariona Bustamante; Patrice Perron; Robert O. Wright; Irva Hertz-Picciotto; Hongmei Zhang; Margaret R. Karagas; Ulrike Gehring; Carmen J. Marsit; Lawrence J. Beilin; Judith M. Vonk; Marjo-Riitta Jarvelin; Anna Bergström; Anne K. Örtqvist; Susan Ewart; Pia M. Villa; Sophie E. Moore; Gonneke Willemsen; Arnout R. L. Standaert; Siri E. Håberg; Thorkild I. A. Sørensen; Jack A. Taylor; Katri Räikkönen; Ivana V. Yang; Katerina Kechris; Tim S. Nawrot; Matt J. Silver; Yun Yun Gong; Lorenzo Richiardi; Manolis Kogevinas; Augusto A. Litonjua; Brenda Eskenazi; Karen Huen; Hamdi Mbarek; Rachel L. Maguire; Terence Dwyer; Martine Vrijheid; Luigi Bouchard; Andrea A. Baccarelli; Lisa A. Croen; Wilfried Karmaus; Denise Anderson; Maaike de Vries; Sylvain Sebert; Juha Kere; Robert Karlsson; Syed Hasan Arshad; Esa Hämäläinen; Michael N. Routledge; Dorret I. Boomsma; Andrew P. Feinberg; Craig J. Newschaffer; Eva Govarts; Matthieu Moisse; M. Daniele Fallin; Erik Melén; Andrew M. Prentice; Eero Kajantie; Catarina Almqvist; Emily Oken; Dana Dabelea; H. Marike Boezen; Phillip E. Melton; Rosalind J. Wright; Gerard H. Koppelman; Letizia Trevisi; Marie-France Hivert; Jordi Sunyer; Monica C. Munthe-Kaas; Susan K. Murphy; Eva Corpeleijn; Joseph Wiemels; Nina Holland; Zdenko Herceg; Elisabeth B. Binder; George Davey Smith; Vincent W. V. Jaddoe; Rolv T. Lie; Wenche Nystad; Stephanie J. London; Debbie A. Lawlor; Caroline L. Relton; Harold Snieder; Janine F. Felix
Source
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Subject
Language
English
ISSN
2041-1723
Abstract
Birthweight has been found to associate with later-life health outcomes. Here the authors perform a meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in the Pregnancy And Childhood Epigenetics Consortium, identifying differentially methylated CpGs in neonatal blood that associate with birthweight.