학술논문
Effects of long-term methylphenidate use on growth and blood pressure: results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS)
Document Type
article
Author
Suzanne McCarthy; Antje Neubert; Kenneth K. C. Man; Tobias Banaschewski; Jan Buitelaar; Sara Carucci; David Coghill; Marina Danckaerts; Bruno Falissard; Peter Garas; Alexander Häge; Chris Hollis; Sarah Inglis; Hanna Kovshoff; Elizabeth Liddle; Konstantin Mechler; Peter Nagy; Eric Rosenthal; Robert Schlack; Edmund Sonuga-Barke; Alessandro Zuddas; Ian C. K. Wong
Source
BMC Psychiatry, Vol 18, Iss 1, Pp 1-10 (2018)
Subject
Language
English
ISSN
1471-244X
Abstract
Abstract Background Concerns have been raised over the safety of methylphenidate (MPH), with regard to adverse effects on growth and blood pressure. Our study investigates whether, and to what extent, methylphenidate use in boys with ADHD is associated with having low body mass index (BMI), having low height, and increased systolic and diastolic blood pressure. Methods Data used for this study stem from the German KiGGS dataset. Three different groups of boys aged 6–15 years were included in the analysis: ADHD patients who used MPH for less than 12 months; ADHD patients who used MPH for 12 months or more; and ADHD patients without current MPH treatment. Each of these three groups was compared to a non-ADHD control group regarding low weight (BMI ≤ 3rd percentile), low height (≤3rd percentile) and raised systolic and diastolic blood pressure. For growth outcomes, boys were categorized according to age (