학술논문
Asynchronous suppression of visual cortex during absence seizures in stargazer mice
Document Type
article
Source
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
Absence epilepsy is associated with frequent generalized spike-wave seizures and loss of awareness. Here the authors use 2-photon calcium imaging of primary visual cortex in a genetic mouse model of absence epilepsy and find that cortical neurons are less active and more loosely coupled to the seizure EEG signature than previously believed.