학술논문
ADRA2A and IRX1 are putative risk genes for Raynaud’s phenomenon
Document Type
article
Author
Source
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Subject
Language
English
ISSN
2041-1723
Abstract
Abstract Raynaud’s phenomenon (RP) is a common vasospastic disorder that causes severe pain and ulcers, but despite its high reported heritability, no causal genes have been robustly identified. We conducted a genome-wide association study including 5,147 RP cases and 439,294 controls, based on diagnoses from electronic health records, and identified three unreported genomic regions associated with the risk of RP (p