부산대학교 도서관

Abstract Background Ongoing rises in obesity prevalence have prompted growing concerns about potential increases in the burden of age‐related musculoskeletal conditions including sarcopenia and sarcopenic obesity. This is of particular concern for future generations of older adults who have lived more of their lives in an obesogenic environment than current generations of older adults. We aimed to study longitudinal associations between body mass index (BMI) and grip strength in midlife using data from a large population‐based sample, the 1970 British Cohort Study (BCS70). Methods BCS70 participants with valid measures of maximum grip strength at age 46 years were included in analyses [3671 males (49%) and 3876 females (51%)]. Using sex‐specific linear regression models, we examined associations of (i) BMI at ages 10, 16, 30, and 46 years; (ii) body fat percentage (BF%) and waist–hip ratio at age 46 years; (iii) BMI gains between 10–16, 16–30, and 30–46; and (iv) age at onset of obesity, with grip strength. Results At age 46 years, mean (standard deviation) grip strength was 48.10 kg (8.98) in males and 29.61 kg (5.81) in females. Higher BMI at all ages was associated with stronger grip, and the scale of associations was greater in males than females from age 16 onwards (Psex interactions