학술논문
Acute microglia ablation induces neurodegeneration in the somatosensory system
Document Type
article
Author
Source
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
Previous studies have shown that depletion of microglia at early developmental stages leads to neuronal death. Here the authors use an inducible system to ablate microglia in adulthood, showing that such depletion leads to ataxia-like behavior and neuronal loss, and identifying the inflammatory components that may contribute.