학술논문

Analysis of risk and protective factors associated with retinal nerve fiber layer defect in a Chinese adult population
Document Type
article
Source
International Journal of Ophthalmology, Vol 16, Iss 3, Pp 427-433 (2023)
Subject
retinal nerve fiber layer defect
retinal nerve fiber layer
age
axial length
hypertension
diabetes mellitus
visual acuity
central anterior chamber depth
Ophthalmology
RE1-994
Language
English
ISSN
2222-3959
2227-4898
Abstract
AIM: To investigate the risk and protective factors associated with the retinal nerve fiber layer defect (RNFLD) in a Chinese adult population. METHODS: This study was a cross-sectional population-based investigation including employees and retirees of a coal mining company in Kailuan City, Hebei Province. All the study participants underwent a comprehensive systemic and ophthalmic examination. RNFLD was diagnosed on fundus photographs. Binary logistic regression was used to investigate the risk and protective factors associated with the RNFLD. RESULTS: The community-based study included 14 440 participants. There were 10 473 participants in our study, including 7120 males (68.0%) and 3353 females (32.0%). The age range was 45-108y, averaging 59.56±8.66y. Totally 568 participants had RNFLD and the prevalence rate was 5.42%. A higher prevalence of RNFLD was associated with older age [P