학술논문

Efficacy of a fixed dose combination of irbesartan and atorvastatin (Rovelito®) in Korean adults with hypertension and hypercholesterolemia
Document Type
article
Author
Source
Drug Design, Development and Therapy, Vol Volume 13, Pp 633-645 (2019)
Subject
Hypertension
Hypercholesterolemia
Fixed-dose combination
Irbesartan
Atorvastatin
Therapeutics. Pharmacology
RM1-950
Language
English
ISSN
1177-8881
Abstract
Sang-Hyun Ihm,1 Jinho Shin,2 Chang-Gyu Park,3 Cheol-Ho Kim4 1Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea; 2Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea; 3Cardiology Division, Korea University Guro Hospital, Seoul, South Korea; 4Department of Internal Medicine, College of Medicine, Seoul National University, Seoul National University Bundang Hospital, Seongnam-si, South Korea Purpose: Coexistence of hypertension (HTN) and hypercholesterolemia is a major synergistic and modifiable risk factor for cardiovascular disease (CVD). Thus, a fixed-dose combination (FDC) of anti-HTN drugs and statins may be useful for treating CVD. This study evaluated the efficacy of an FDC of irbesartan and atorvastatin (Rovelito®) in Korean patients.Patients and methods: Patients with HTN and hypercholesterolemia were screened for this prospective, observational, descriptive, multi-center, phase IV study. Eligible patients were administered with Rovelito for 3 months. Dose adjustment was allowed based on the physician’s discretion. Blood pressure (BP) goal was