학술논문
Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2
Document Type
article
Author
Shihui Sun; Hongjing Gu; Lei Cao; Qi Chen; Qing Ye; Guan Yang; Rui-Ting Li; Hang Fan; Yong-Qiang Deng; Xiaopeng Song; Yini Qi; Min Li; Jun Lan; Rui Feng; Yan Guo; Na Zhu; Si Qin; Lei Wang; Yi-Fei Zhang; Chao Zhou; Lingna Zhao; Yuehong Chen; Meng Shen; Yujun Cui; Xiao Yang; Xinquan Wang; Wenjie Tan; Hui Wang; Xiangxi Wang; Cheng-Feng Qin
Source
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
In this study, Qin et al. present a murine-adapted SARS-CoV-2 strain, MASCp36, as a model for studying the pathogenicity, evolution and adaptation of the virus to human and animal hosts.