학술논문
miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis
Document Type
article
Source
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Subject
Language
English
ISSN
2041-1723
Abstract
The transcription factor CHOP/GADD153 regulates apoptosis in response to the unfolded protein response. Here the authors show that CHOP/GADD153 regulates the expression of miR-216b, which targets c-Jun and sensitizes cells to ER stress-dependent apoptosis.