학술논문
Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders
Document Type
article
Author
Yalda Afshar; Jiantong Dong; Pan Zhao; Lei Li; Shan Wang; Ryan Y. Zhang; Ceng Zhang; Ophelia Yin; Christina S. Han; Brett D. Einerson; Tania L. Gonzalez; Huirong Zhang; Anqi Zhou; Zhuo Yang; Shih-Jie Chou; Na Sun; Ju Cheng; Henan Zhu; Jing Wang; Tiffany X. Zhang; Yi-Te Lee; Jasmine J. Wang; Pai-Chi Teng; Peng Yang; Dongping Qi; Meiping Zhao; Myung-Shin Sim; Ruilian Zhe; Jeffrey D. Goldstein; John Williams; Xietong Wang; Qingying Zhang; Lawrence D. Platt; Chang Zou; Margareta D. Pisarska; Hsian-Rong Tseng; Yazhen Zhu
Source
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
Placenta accreta spectrum (PAS) is a high-risk obstetrical complication associated with significant morbidity and mortality. Here the authors discover a uniquely high prevalence of circulating trophoblasts clusters in PAS and explore their diagnostic potential to augment current diagnostic modalities for the early detection of PAS.