학술논문
Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques
Document Type
article
Author
Victoria E. K. Walker-Sperling; Noe B. Mercado; Abishek Chandrashekar; Erica N. Borducchi; Jinyan Liu; Joseph P. Nkolola; Mark Lewis; Jeffrey P. Murry; Yunling Yang; Romas Geleziunas; Merlin L. Robb; Nelson L. Michael; Maria G. Pau; Frank Wegmann; Hanneke Schuitemaker; Emily J. Fray; Mithra R. Kumar; Janet D. Siliciano; Robert F. Siliciano; Dan H. Barouch
Source
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Antiretroviral therapy alone is insufficient in curing HIV-1 infection, due to latent viral reservoir persistency. Here, authors explore the post-virologic control of combining active and passive immunisation with vesatolimod, in a SHIV-infected rhesus macaque model.