학술논문

No evidence of increasing Haemophilus influenzae non-b infection in Australian Aboriginal children
Document Type
article
Source
International Journal of Circumpolar Health, Vol 72, Iss 0, Pp 1-6 (2013)
Subject
Haemophilus influenza
oceanic ancestry group
epidemiology
Arctic medicine. Tropical medicine
RC955-962
Language
English
ISSN
2242-3982
Abstract
Background. High, or increasing, rates of invasive Haemophilus influenzae (Hi) type a disease have been reported from North American native children from circumpolar regions, raising the question of serotype replacement being driven by vaccination against Hi type b (Hib). Indigenous Australians from remote areas had high rates of invasive Hib disease in the past, comparable to those in North American Indigenous populations. Objective. Evaluate incidence rates of invasive Hi (overall and by serotype) in Indigenous Australian children over time. Design. Descriptive study of Hi incidence rates by serotype, in the Northern Territory (NT) and South Australia (SA) from 2001 to 2011. Comparison of NT data with a study that was conducted in the NT in 1985–1988, before Hib vaccine was introduced. Results. The average annual rate of invasive Hi type a (Hia) disease in Indigenous children aged