학술논문
Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference
Document Type
article
Author
Laura J. Corbin; Vanessa Y. Tan; David A. Hughes; Kaitlin H. Wade; Dirk S. Paul; Katherine E. Tansey; Frances Butcher; Frank Dudbridge; Joanna M. Howson; Momodou W. Jallow; Catherine John; Nathalie Kingston; Cecilia M. Lindgren; Michael O’Donavan; Stephen O’Rahilly; Michael J. Owen; Colin N. A. Palmer; Ewan R. Pearson; Robert A. Scott; David A. van Heel; John Whittaker; Tim Frayling; Martin D. Tobin; Louise V. Wain; George Davey Smith; David M. Evans; Fredrik Karpe; Mark I. McCarthy; John Danesh; Paul W. Franks; Nicholas J. Timpson
Source
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
Recall-by-Genotype (RbG) is an approach to recall participants from genetic studies based on their specific genotype for further, more extensive phenotyping. Here, the authors discuss examples of RbG as well as practical and ethical considerations and provide an online tool to aid in designing RbG studies.