학술논문

Development of a novel index to characterise arterial dynamics using ultrasound imaging.
Document Type
article
Source
PLoS ONE, Vol 16, Iss 3, p e0248043 (2021)
Subject
Medicine
Science
Language
English
ISSN
1932-6203
Abstract
Abdominal aortic aneurysms (AAA) are associated with systemic inflammation and endothelial dysfunction. We previously reported flow mediated dilatation (FMD) of the brachial artery as a predictor of AAA growth. We hence hypothesised that other physical characteristics of the brachial artery correlate with AAA growth. Using a prospectively cohort of AAA patients, we devised a 'brachial artery relaxation index' (BARI) and examined its role as a biomarker for AAA growth. However, no correlation between BARI and future aneurysm growth was observed (p = 0.45). Therefore, our investigations did not substantiate the hypothesis that other physical characteristics of the brachial artery predicts AAA growth.