학술논문
Changes in serotype prevalence of Streptococcus pneumoniae in Southampton, UK between 2006 and 2018
Document Type
article
Author
Source
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Subject
Language
English
ISSN
2045-2322
Abstract
Abstract Streptococcus pneumoniae continues to cause significant disease burden. Whilst pneumococcal conjugate vaccines (PCV) have substantially reduced this burden, serotype replacement partially negates this success due to increased disease associated with non-vaccine serotypes (NVTs). Continued surveillance is therefore essential to provide crucial epidemiological data. Annual cross-sectional surveillance of paediatric pneumococcal carriage was started in Southampton, UK following PCV7 roll-out in 2006. Nasopharyngeal swabs were collected from children