학술논문
Biological sample donation and informed consent for neurobiobanking: Evidence from a community survey in Ghana and Nigeria.
Document Type
article
Author
Arti Singh; Oyedunni Arulogun; Joshua Akinyemi; Michelle Nichols; Benedict Calys-Tagoe; Babatunde Ojebuyi; Carolyn Jenkins; Reginald Obiako; Albert Akpalu; Fred Sarfo; Kolawole Wahab; Adeniyi Sunday; Lukman F Owolabi; Muyiwa Adigun; Ibukun Afolami; Olorunyomi Olorunsogbon; Mayowa Ogunronbi; Ezinne Sylvia Melikam; Ruth Laryea; Shadrack Asibey; Wisdom Oguike; Lois Melikam; Abdullateef Sule; Musibau A Titiloye; Isah Suleiman Yahaya; Abiodun Bello; Rajesh N Kalaria; Ayodele Jegede; Mayowa Owolabi; Bruce Ovbiagele; Rufus Akinyemi
Source
PLoS ONE, Vol 17, Iss 8, p e0267705 (2022)
Subject
Language
English
ISSN
1932-6203
Abstract
IntroductionGenomic research and neurobiobanking are expanding globally. Empirical evidence on the level of awareness and willingness to donate/share biological samples towards the expansion of neurobiobanking in sub-Saharan Africa is lacking.AimsTo ascertain the awareness, perspectives and predictors regarding biological sample donation, sharing and informed consent preferences among community members in Ghana and Nigeria.MethodsA questionnaire cross-sectional survey was conducted among randomly selected community members from seven communities in Ghana and Nigeria.ResultsOf the 1015 respondents with mean age 39.3 years (SD 19.5), about a third had heard of blood donation (37.2%, M: 42.4%, F: 32.0%, p = 0.001) and a quarter were aware of blood sample storage for research (24.5%; M: 29.7%, F: 19.4%, p = 0.151). Two out of ten were willing to donate brain after death (18.8%, M: 22.6%, F: 15.0%, pConclusionThere is a greater need for research attention in the area of brain banking and informed consent. Improved context-sensitive public education on neurobiobanking and informed consent, in line with the sociocultural diversities, is recommended within the African sub region.