학술논문

Effects of exercise training on autonomic modulation and mood symptoms in patients with obstructive sleep apnea
Document Type
article
Source
Brazilian Journal of Medical and Biological Research
Subject
Exercise
Cardiac autonomic modulation
Spontaneous baroreflex sensitivity
Mood symptoms
Obstructive sleep apnea
Medicine (General)
R5-920
Biology (General)
QH301-705.5
Language
English
ISSN
1414-431X
1414-431x
Abstract
We evaluated the effects of exercise training (ET) on the profile of mood states (POMS), heart rate variability, spontaneous baroreflex sensitivity (BRS), and sleep disturbance severity in patients with obstructive sleep apnea (OSA). Forty-four patients were randomized into 2 groups, 18 patients completed the untrained period and 16 patients completed the exercise training (ET). Beat-to-beat heart rate and blood pressure were simultaneously collected for 5 min at rest. Heart rate variability (RR interval) was assessed in time domain and frequency domain (FFT spectral analysis). BRS was analyzed with the sequence method, and POMS was analyzed across the 6 categories (tension, depression, hostility, vigor, fatigue, and confusion). ET consisted of 3 weekly sessions of aerobic exercise, local strengthening, and stretching exercises (72 sessions, achieved in 40±3.9 weeks). Baseline parameters were similar between groups. The comparisons between groups showed that the changes in apnea-hypopnea index, arousal index, and O2 desaturation in the exercise group were significantly greater than in the untrained group (P