학술논문
Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility
Document Type
article
Author
S. Dhara; S. Chhangawala; H. Chintalapudi; G. Askan; V. Aveson; A. L. Massa; L. Zhang; D. Torres; A. P. Makohon-Moore; N. Lecomte; J. P. Melchor; J. Bermeo; A. Cardenas; S. Sinha; D. Glassman; R. Nicolle; R. Moffitt; K. H. Yu; S. Leppanen; S. Laderman; B. Curry; J. Gui; V. P. Balachandran; C. Iacobuzio-Donahue; R. Chandwani; C. S. Leslie; S. D. Leach
Source
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
ATAC-seq allows for the investigation of chromatin accessibility, a feature which can have important implications for gene regulation. Here the authors present ATAC-array to assess accessibility in human tumours and based on this predict disease prognosis.