학술논문

Late-onset thyrotoxicosis after the cessation of amiodarone
Document Type
article
Source
Indian Pacing and Electrophysiology Journal, Vol 20, Iss 6, Pp 265-268 (2020)
Subject
Amiodarone
Thyrotoxicosis
Atrial fibrillation
Ventricular arrhythmia
Drug toxicity
Diseases of the circulatory (Cardiovascular) system
RC666-701
Language
English
ISSN
0972-6292
Abstract
Introduction: Amiodarone is a highly effective antiarrhythmic-drug with well recognized toxic side-effects. The effects of the drug late in patients with atrial fibrillation (AF) is not well described. Methods and results: We present a single centre prospectively collected series of patients with thyrotoxicosis occurring late after the cessation of amiodarone. Between 2006 and 2018, 8 patients were identified with amiodarone induced thyrotoxicosis (AIT). Amiodarone was prescribed for AF in 7 patients and ventricular tachycardia in 1 patient. Mean duration of therapy was 329 [42–1092] days, mean dose of 200 ± 103.5 mg/day. Amiodarone use was short term (