학술논문
Monitoring peripheral hemodynamic response to changes in blood pressure via photoacoustic imaging
Document Type
article
Author
Source
Photoacoustics, Vol 26, Iss , Pp 100345- (2022)
Subject
Language
English
ISSN
2213-5979
Abstract
Chronic wounds and amputations are common in chronic kidney disease patients needing hemodialysis (HD). HD is often complicated by drops in blood pressure (BP) called intra-dialytic hypotension. Whether intra-dialytic hypotension is associated with detectable changes in foot perfusion, a risk factor for wound formation and impaired healing remains unknown. Photoacoustic (PA) imaging is ideally suited to study perfusion changes. We scanned the feet of 20 HD and 11 healthy subjects. HD patients were scanned before and after a dialysis session whereas healthy subjects were scanned twice at rest and once after a 10 min exercise period while BP was elevated. Healthy (r = 0.70, p