학술논문

Detection of cognitive impairment using self-rated AD8 and informant-reported AD8
Document Type
article
Source
Journal of the Formosan Medical Association, Vol 117, Iss 1, Pp 42-47 (2018)
Subject
area under the curve
cognitive disorders
dementia
mild cognitive impairment
self-report
Medicine (General)
R5-920
Language
English
ISSN
0929-6646
Abstract
Background/Purpose: Screening of dementia can help to initiate proper management of the disorder. The use of the Ascertain Dementia 8-item Questionnaire (AD8) in screening has been promoted in Taiwan recently. The purpose of this study was to compare the psychometric properties and appropriateness of informant-reported and self-rated AD8 in cognitive impairment screening in Taiwan. Methods: The AD8 were administered to 153 participants and their informants recruited from two neurology out-patient clinics. The discriminative abilities for early cognitive impairment [Clinical Dementia Rating scale (CDR) 0.5 and 1] of informant-based and self-rating AD8 were determined and compared with their areas under the receiver operating curve. κ coefficients representing the agreement between self-rated and informant-reported AD8 scores were also calculated. Results: Participants and their informants were aged 76.9 years and 56.0 years on average, respectively. Only informant-reported AD8 was significantly associated with CDR level (Spearman ρ=0.469, p