학술논문
Clinical spectrum and risk factors for mortality among seawater and freshwater critically ill drowning patients: a French multicenter study
Document Type
article
Author
Florian Reizine; Agathe Delbove; Alexandre Dos Santos; Laetitia Bodenes; Pierre Bouju; Pierre Fillâtre; Aurélien Frérou; Guillaume Halley; Olivier Lesieur; Maud Jonas; Florian Berteau; Jean Morin; David Luque-Paz; Rémy Marnai; Anthony Le Meur; Cécile Aubron; Jean Reignier; Jean-Marc Tadié; Arnaud Gacouin
Source
Critical Care, Vol 25, Iss 1, Pp 1-9 (2021)
Subject
Language
English
ISSN
1364-8535
Abstract
Abstract Background Drowning is a global threat and one of the leading causes of injury around the world. The impact of drowning conditions including water salinity on patients’ prognosis remains poorly explored in Intensive Care Units (ICUs) patients. Methods We conducted a retrospective multicenter study on patients admitted to 14 ICUs in the west of France from January 2013 to January 2020. We first compared demographic and clinical characteristics at admission as well as clinical courses of these patients according to the salinity of drowning water. Then, we aimed to identify variables associated with 28-day survival using a Cox proportional hazard model. Results Of the 270 consecutive included patients, drowning occurred in seawater in 199 patients (73.7%) and in freshwater in 71 patients (26.3%). Day-28 mortality was observed in 55 patients (20.4%). Freshwater was independently associated with 28-day mortality (Adjusted Hazard Ratio (aHR) 1.84 [95% Confidence Interval (CI) 1.03–3.29], p = 0.04). A higher proportion of freshwater patients presented psychiatric comorbidities (47.9 vs. 19.1%; p