학술논문

Impact of myo-inositol treatment in women with polycystic ovary syndrome in assisted reproductive technologies
Document Type
article
Source
Reproductive Health, Vol 18, Iss 1, Pp 1-8 (2021)
Subject
Polycystic ovary syndrome (PCOS)
Myo-inositol
In vitro fertilization
Intracytoplasmic sperm injection (IVF-ICSI)
Embryo quality
Pregnancy
Gynecology and obstetrics
RG1-991
Language
English
ISSN
1742-4755
Abstract
Abstract Polycystic ovary syndrome (PCOS) is marked in 30 to 40% by insulin resistance and hyperandrogenism. Myo-inositol (MI) increases insulin sensitivity, decreases hyperandrogenism and improves the menstrual cycle. Its effect during assisted reproductive technologies (ART) has been studied by many authors. We conducted a review of the literature on the impact of MI administration in PCOS women in assisted reproductive technologies. Myo-inositol is effective in normalizing ovarian function, improving oocyte and embryo quality in PCOS, however further evaluations by large multicentre randomized controlled trials are needed to assess the clinical pregnancy and live birth rates in ART.