학술논문

Severe Toxic Epidermal Necrolysis and Drug Reaction with Eosinophilia and Systemic Symptoms Overlap Syndrome Treated with Benralizumab: A Case Report
Document Type
article
Source
Case Reports in Dermatology, Vol 14, Iss 2, Pp 203-209 (2022)
Subject
drug reaction with eosinophilia and systemic symptoms
toxic epidermal necrolysis
benralizumab
il-5 blocker
Dermatology
RL1-803
Language
English
ISSN
1662-6567
Abstract
TEN/DRESS overlap syndrome can be difficult to diagnose, especially if it is masked by comorbidities in critically ill patients in intensive care units. The existing therapy for the two conditions is also a major challenge for the treating team. A possible alternative, especially for refractory cases, is benralizumab as an IL-5-receptor alpha-chain-specific humanized monoclonal antibody (IgG1k). We are able to show a successful treatment in this case report.