학술논문
A mutation in the atrial-specific myosin light chain gene (MYL4) causes familial atrial fibrillation
Document Type
article
Author
Source
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Subject
Language
English
ISSN
2041-1723
Abstract
Here, Michael Gollob and colleagues perform a whole exome sequencing study to identify a mutation in the atrial-specific myosin light chain gene MYL4 in a small family with autosomal dominant familial atrial fibrillation. They also test the functionality of this MYL4mutation in zebrafish cardiac function and recapitulate disease-related phenotypes.