학술논문

Molecular resolution imaging by post-labeling expansion single-molecule localization microscopy (Ex-SMLM)
Document Type
article
Source
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Subject
Science
Language
English
ISSN
2041-1723
Abstract
Previous attempts to combine expansion microscopy (ExM) and single molecule localisation microscopy (SMLM) have proved challenging. Here the authors show that post-labelling Ex-SMLM improves labelling efficiency, reduces linkage error, and preserves ultrastructural details.