학술논문
LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation
Document Type
article
Author
Source
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
Subject
Language
English
ISSN
2041-1723
Abstract
miR-205 is known to have context-dependent tumor suppressive or oncogenic roles. Here, the authors report the host gene of miR-205, MIR205HG as a nuclear lincRNA that maintains the basal identity of prostate cell and prevents luminal cell differentiation via the repression of interferon responsive genes.