학술논문
Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease
Document Type
article
Author
Jody Phelan; Paula Josefina Gomez-Gonzalez; Nuria Andreu; Yosuke Omae; Licht Toyo-Oka; Hideki Yanai; Reiko Miyahara; Supalert Nedsuwan; Paola Florez de Sessions; Susana Campino; Neneh Sallah; Julian Parkhill; Nat Smittipat; Prasit Palittapongarnpim; Taisei Mushiroda; Michiaki Kubo; Katsushi Tokunaga; Surakameth Mahasirimongkol; Martin L. Hibberd; Taane G. Clark
Source
Nature Communications, Vol 14, Iss 1, Pp 1-7 (2023)
Subject
Language
English
ISSN
2041-1723
Abstract
Few genetic loci have been associated with tuberculosis infection, possibly because of the influence of genetic variation in the pathogen. Here, the authors integrate human and Mycobacterium tuberculosis genetics to find genome-genome interactions associated with infection.