학술논문
Community recommendations on cryoEM data archiving and validation
Document Type
article
Author
Gerard J. Kleywegt; Paul D. Adams; Sarah J. Butcher; Catherine L. Lawson; Alexis Rohou; Peter B. Rosenthal; Sriram Subramaniam; Maya Topf; Sanja Abbott; Philip R. Baldwin; John M. Berrisford; Gérard Bricogne; Preeti Choudhary; Tristan I. Croll; Radostin Danev; Sai J. Ganesan; Timothy Grant; Aleksandras Gutmanas; Richard Henderson; J. Bernard Heymann; Juha T. Huiskonen; Andrei Istrate; Takayuki Kato; Gabriel C. Lander; Shee-Mei Lok; Steven J. Ludtke; Garib N. Murshudov; Ryan Pye; Grigore D. Pintilie; Jane S. Richardson; Carsten Sachse; Osman Salih; Sjors H. W. Scheres; Gunnar F. Schroeder; Carlos Oscar S. Sorzano; Scott M. Stagg; Zhe Wang; Rangana Warshamanage; John D. Westbrook; Martyn D. Winn; Jasmine Y. Young; Stephen K. Burley; Jeffrey C. Hoch; Genji Kurisu; Kyle Morris; Ardan Patwardhan; Sameer Velankar
Source
IUCrJ, Vol 11, Iss 2, Pp 140-151 (2024)
Subject
Language
English
ISSN
2052-2525
20522525
20522525
Abstract
In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for the deposition and validation of cryoEM structures, with a focus on single-particle analysis. The meeting was attended by 47 experts in data processing, model building and refinement, validation, and archiving of such structures. This report describes the workshop's motivation and history, the topics discussed, and the resulting consensus recommendations. Some challenges for future methods-development efforts in this area are also highlighted, as is the implementation to date of some of the recommendations.