학술논문
A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset
Document Type
article
Author
Dorothée Selimoglu-Buet; Julie Rivière; Hussein Ghamlouch; Laura Bencheikh; Catherine Lacout; Margot Morabito; M’boyba Diop; Guillaume Meurice; Marie Breckler; Aurélie Chauveau; Camille Debord; Franck Debeurme; Raphael Itzykson; Nicolas Chapuis; Christophe Willekens; Orianne Wagner-Ballon; Olivier A. Bernard; Nathalie Droin; Eric Solary
Source
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
A decrease in the fraction of non-classical monocytes is a hallmark of chronic myelomonocytic leukaemia. Taking advantage of this abnormal situation, the authors identify a mechanistic link between miR-150 and TET3 as being involved in monocyte subset generation.