학술논문
Impact of Coronary Artery Disease Severity Assessed With the SYNTAX Score on Outcomes Following Transcatheter Aortic Valve Replacement
Document Type
article
Author
Jean‐Michel Paradis; Jonathon M. White; Philippe Généreux; Marina Urena; Darshan Doshi; Tamim Nazif; Rebecca Hahn; Isaac George; Omar Khalique; Kishore Harjai; Laura Lasalle; Benoit M. Labbé; Robert DeLarochellière; Daniel Doyle; Éric Dumont; Siamak Mohammadi; Martin B. Leon; Josep Rodés‐Cabau; Susheel Kodali
Source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 2 (2017)
Subject
Language
English
ISSN
2047-9980
Abstract
BackgroundThe influence of coronary artery disease (CAD) on clinical and echocardiographic outcomes after transcatheter aortic valve replacement (TAVR) is still controversial. We sought to evaluate the impact of CAD severity as measured by the SYNTAX score (SS) on patients undergoing TAVR. Methods and ResultsA total of 377 patients who underwent TAVR in 2 high‐volume centers in North America were included in our retrospective analysis. A blinded angiographic core laboratory calculated the SS on all available coronary angiograms with the use of quantitative coronary analysis. Patients were stratified into 4 groups: (1) no CAD (SS=0); (2) low SS (SS between 1 and 22); (3) intermediate SS (SS between 23 and 32); and (4) high SS (SS ≥33). Patients who had undergone percutaneous coronary intervention within 6 months prior to TAVR were separated into 2 categories based on their residual SS (