학술논문
Persistent elevation of plasma vitamin B12 is strongly associated with solid cancer
Document Type
article
Author
Source
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Subject
Language
English
ISSN
2045-2322
Abstract
Abstract Elevated plasma vitamin B12 has been associated with solid cancers, based on a single B12 measurement. We evaluated the incidence of solid cancers following B12 measurement in patients with persistent elevated B12, compared to patients without elevated B12 and to patients with non-persistent elevated B12. The study population included patients with at least two plasma B12 measurements without already known elevated-B12-related causes. Patients with elevated plasma B12 (≥ 1000 ng/L) at first measurement (n = 344) were matched for age and sex with patients having 2 normal B12 measurements (