학술논문

The authors’ response
Document Type
article
Source
Journal of Intensive Care, Vol 8, Iss 1, Pp 1-2 (2020)
Subject
Cerebral edema
Subarachnoid hemorrhage
Hyperosmolar therapy
Hyperchloremia
Acute kidney injury
Neurocritical care
Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
Language
English
ISSN
2052-0492
Abstract
Abstract In response to comments raised, we acknowledge the shortcomings of our study. It is a small study. However, it is a pilot study, which is not meant to create generalizable data, rather to explore new potential directions. To this end, our conclusions were clearly supported by the results. We demonstrated that administration of 16.4% NaCl/Na-acetate solution was feasible, safe, and was associated with lower rates of AKI. We share the call that large RCTs are required to follow this pilot study and hope that our data will stimulate the ongoing discussion regarding the role of chloride in AKI mechanism.