학술논문
Diagnosis and Treatment of Irritable Bowel Syndrome: Clinical Recommendations of the Russian Gastroenterological Association and Association of Coloproctologists of Russia
Document Type
article
Author
V. T. Ivashkin; I. V. Maev; Yu. A. Shelygin; E. K. Baranskaya; S. S. Belous; E. A. Belousova; A. G. Beniashvili; S. V. Vasilyev; A. V. Veselov; E. G. Grigoryev; N. V. Kostenko; V. N. Kashnikov; V. F. Kulikovskiy; I. D. Loranskaya; O. S. Lyashenko; E. A. Poluektova; V. G. Rumyantsev; V. M. Timerbulatov; O. Yu. Fomenko; D. A. Khubezov; E. Yu. Chashkova; G. I. Chibisov; M. V. Shapina; A. A. Sheptulin; O. S. Shifrin; A. S. Trukhmanov; O. P. Alekseeva; S. A. Alekseenko; A. Yu. Baranovsky; O. Yu. Zolnikova; N. V. Korochanskaya; S. N. Mammayev; I. B. Khlynov; V. V. Tsukanov
Source
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 31, Iss 5, Pp 74-95 (2022)
Subject
Language
Russian
ISSN
1382-4376
2658-6673
2658-6673
Abstract
Aim. Current clinical recommendations accentuate current methods for the diagnosis and treatment of irritable bowel syndrome (IBS).Key points. IBS is a functional bowel disorder manifested with recurrent, at least weekly, abdominal pain with the following attributes (any two leastwise): link to defecation, its frequency or stool shape. The symptoms are expected to persist for at minimum three months in a total six-month follow-up. Similar to other functional gastrointestinal (GI) disorders, IBS can be diagnosed basing on the patient symptoms compliance with Rome IV criteria, provided the absence of potentially symptom-causative organic GI diseases. Due to challenging differential diagnosis, IBS can be appropriately established per exclusionem, with pre-examination as follows: general and biochemical blood tests; tissue transglutaminase IgA/IgG antibody tests; thyroid hormones test; faecal occult blood test; hydrogen glucose/ lactulose breath test for bacterial overgrowth; stool test for enteric bacterial pathogens and Clostridium difficile A/B toxins; stool calprotectin test; abdominal ultrasound; OGDS, with biopsy as appropriate; colonoscopy with biopsy. The IBS sequence is typically wavelike, with alternating remissions and exacerbations often triggered by psychoemotional stress. Treatment of IBS patients includes dietary and lifestyle adjustments, various-class drug agents prescription and psychotherapeutic measures.Conclusion. Adherence to clinical recommendations can facilitate timely diagnosis and improve medical aid quality in patients with different clinical IBS variants.