학술논문
Parvalbumin-expressing interneurons coordinate hippocampal network dynamics required for memory consolidation
Document Type
article
Author
Source
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Subject
Language
English
ISSN
2041-1723
Abstract
Episodic memory consolidation requires activity in hippocampal area CA1. Here the authors report that pharmacogenetic inhibition of CA1 PV+ interneuron firing after fear learning blocks memory consolidation and disrupts associated enhancement in network oscillations and stabilization of functional connectivity patterns.